Evaluation of fatty acid and mineral profiles and bioaccessibility of diosgenin in different types of Peruvian maca (Lepidium meyenii Walp)

Francisca das Chagas do Amaral Souza, Edson Pablo da Silva, Leonardo Gomes Sanders Moura, Jaime Paiva Lopes Aguiar

Abstract


 The present work aimed to study the bioaccessibility of diosgenin, fatty acid and mineral profile in different types of Peruvian maca (Lepidium meyenii Walp). Analyzes of minerals, fatty acids, saponins and bioaccessibility of diosgenin were performed. For minerals the values were detected: commercial litter (MC) 490.65mg / 100g of Ca, 1472.65mg / 100g of K, in red litter (MV) 1478.25mg / 100g of K and 670.25mg / 100g of Ca, yellow yellow (MA) 875.65mg / 100g Ca, 1215.25mg / 100g K. The highest concentrations of fatty acids were related to the unsaturated portion. % oleic acid in the red stretcher. Regarding the saponin and diosgenin content, the commercial litter presented the highest contents 250.33mg / 100g for saponins, and 340.56µg / ml for diosgenin. These results emphasize the importance of the consumption of this nutrient-rich vegetable with effective action on human metabolism (p <0.05).


Keywords


Bioactive compounds; Saponins; HPLC; Bioprospecting; Food chemistry.

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References


Balamurugan, E., Manivannan, J., Sivasubramanian, J. & Arunagiri, P. (2013). Diosgenin prevents hepatic oxidative stress, lipid peroxidation and molecular alterations in chronic renal failure rats. Int. J. Nutr. Pharmacol. Neurol. Dis., 3, 289.

Bligh, E.G. & Dyer, W.J. (1959). A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol, 37, 911-917.

Chen, X., Sood, S., Yang, C.S. & Li, N., et al. (2006). Five-lipoxygenase pathway of arachidonic acid metabolism in carcino-genesis and cancer chemoprevention. Current Cancer Drug Targets, 6, 613–622.

Chen PS, Shih YW, Huang HC & Cheng HW., et al (2011). Diosgenin, a steroidal saponin, inhibits migration and invasion of human prostate cancer PC-3 cells by reducing matrix metalloproteinases expression. PLoS One, 6(5), e20164.

Cozza, K. L. & Costa, JAV. (2000). Lipídios em Spirulina. Vetor, Rio Grande, 10, 69-80.

Desai, S., Tatke, P. & Gabhe SY. (2015). Quantification of diosgenin in extracts and formulations containing Solanum nigrum. Int J Pharm Sci Res, 6(2), 676-81. doi: 10.13040/IJPSR.0975-8232.6(2).676-81.

Dufour, C. & Loonis, M. (2005). Regio- and stereoselective oxidation of linoleic acid bound to serum albumin: identification by ESI–mass spectrometry and NMR of the oxidation products. Chem. Phys. Lipids, 138, 60-68.

Dini, A., Miglioulo, G., Rastrelli, L., Saturnino, P. & Schettino, P. (1994). Chemical composition of Lepidium meyenii. Food Chemistry, 49, 347-349.

Dini, I., Tenore, G. C. & Dini, A. (2002). Glucosinolates from maca (Lepidium meyenii). Biochemical Systematic and Ecology, 30, 1087–1090.

Esparza, E., Hadzich, A., Kofer, W., Mithofer, A. & Gosio, E.G. (2015). Bioactive maca (Lepidium meyenii) alkamides are a result of traditional Andean postharvest drying practices. Phytochemistry, 116, 138–148.

Ferreira, D. F. (2010). Sisvar: sistema de análise de variância. Versão 5.3. Lavras: Ufla.

Food Ingredients Brasil. (2008, No. 4). Retrieved from www.revista-fi.com

Nunes C. & Pinheiro, A.C.M. 2017. SensoMaker, Version 1.91 UFLA, Lavras.

Furstenberger, G., Krieg, P., Müller-Decker, K. & Habenicht, A.J. (2006). What are cyclooxygenases and lipoxygenases doing in the driver’s seat of carcinogenesis? International Journal of Cancer, 119, 2247–2254.

Gonzales, G.F., Nieto, J., Rubio, J. & Gasco, M. (2006). Effect of Black maca (Lepidium meyenii) on one spermatogenic cycle in rats. Andrologia, 38, 166–72.

Hsu, K., Chang, C., Tsai, H., Tsai, F., et al. (2008). Effects of yam and diosgenina on calpain systems in skeletal muscle of ovariectomized rats. Taiwan Journal of Obstetrics and Gynecology, 47(2), 180-185.

Léger, D.Y., Liagre, B., Corbière, C. & Cook-Moreau, J. (2004). Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA 2 and COX-2 overexpression. International Journal of Oncology, 25, 555.

Li, J., Liu, X., Guo, M., Liu, Y., Liu, S. & Yao, S. (2005). Electrochemical study of breast cancer cells MCF-7 and its application in evaluating the effect of diosgenin. Anal. Sci, 21(5), 561-4.

Moalic, S., Liagrea, B., Corbièrea, C. & Bianchet, A. (2001). A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells. FEBS Letters, 506, 225.

Omran, S. S., Ashton, J., & Stathopoulos, C. E. (2010). Effect of maca (Lepidium meyenii) on some physical characteristics of cereal and root starches. International Food Research Journal, 17(4), 1085-1093.

Pereira, A.S. et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM. Disponível em: https://repositorio.ufsm.br/bitstream/handle/1/15824/ Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1. Acesso em: 19 Abril 2020.

Piacente, S., Carbone, V., Plaza, A., Zampelli, A. & Pizza, C. (2002). Investigation of the tuber constituents of maca (Lepidium meyenii Walp.). J. Agric. Food Chem, 50, 5621–5625.

Quiros, C.F. & Aliaga, R.C. (1997). Andean Roots and Tubers: Ahipa, Arracacha, Maca, and Yacon, Herman M, Heller J (eds.) Rome: International Plant Genetic Resources Institute, 174–197.

Raju, J. & Mehta, R., (2009). Cancer chemopreventive and therapeutic effects of diosgenin, a food saponin. Nutr Cancer, 61(1), 27-35.

Tellez, M.R., Khan, A. I., Kobaisy, M., Schrader, K. K., Dayan, E. F. & Osbrink, W. (2002). Composition of the essential oil of Lepidium meyenii (Walp). Phytochemistry 61, 149–155.

Tello, J., Hermann, M. & Calderon, A. (1992). La Maca (Lepidium meyenii Walp.) cultivo alimenticio potencial para las zonas altoandinas. Boletın Lima, 14, 59.

Yang, B. & Kallio, H. (2001). Fatty acid composition of lipids in sea buckthorn (Hippophae ̈rhamnoides L.) berries of different origins. J. Agric. Food Chem. 49, 1939–1947.

Yllescas M. (1994). Estudio quımico y Fisicoquımico de tres ecotipos de Lepidium meyenii procedentes de Carhuamayo. Lima, Peru: Facultad de Farmacia y Bioquımica, Universidad Nacional Mayor de San Marcos.

Reyna-Villasmil, E., Mejia, J., Reyna Villasmil, N., Torres, D., Peña, E., Colmenares, M., Delgado, O. & Santos, A. (2008). Efecto de diosgenina en la proteína C reactiva y homocisteína en pacientes menopáusicas. Clin Invest Gin Obst, 35(4),120-5.

Rubio, J., Caldas, M., Davila, S., Gasco, M. & Gonzales, GF. (2006). Effect of three different cultivars of Lepidium meyenii (Maca) on learning and depression in ovariectomized mice. BMC Complement Altern Med, 6, 23.

Sánchez Mendoza, N. A, Jiménez M. Cr., Cardador Martínez, A., Martín del Campo B., Sandra & Dávila O. Gloria. (2016). Caracterización física, nutricional y no nutricional de las semillas de Inga paterno. Revista chilena de nutrición, 43(4), 400-407. https://dx.doi.org/10.4067/S0717-75182016000400010.

Shi, J., Xue, S.J., Li, D., Ma, Y., Kakuda, Y. & Lan, Y. (2009). Kinetic study of saponins B stability in navy beans under different processing conditions. J Food Eng, 93, 59-65.

Tang, W., Jin, L., Xie, L., Huang, J., Wang, N., Chu, B., Dai, X., Liu, Y., Wang, R. & Zhang, Y. (2017). Structural characterization and antifatigue effect in vivo of maca (Lepidium meyenii Walp) polysaccharide. Journal of Food Science, 82(3), 757-764.

http:// dx.doi.org/10.1111/1750-3841.13619. PMid:28231388.

Vigo, C.L.S., Narita, E. & Marques, L. C. (2003). Validação da metodologia de quantificação espectrofotométrica das saponinas de Pfaffia glomerata (Spreng.) Pedersen-Amaranthaceae. Revista Brasileira de Farmacognosia, 13, 46-49.

Wang Y, Zhang Y, Zhu Z, Zhu S. & Li Y. (2007). Exploration of the correlation between structure, hemolytic activity and cytotoxicity of steroid saponins. Bioorg Med Chem. 15, 2538-2542.

Wannes, W.A. & Marzouk, B. (2016). Characterization of myrtle seed (Myrtus communis var. baetica) as a source of lipids, phenolics, and antioxidant activities. Journal of food and drug analysis, 24, 316 e 323.

Wood, R. J. & Zheng, J. J. (1997). High dietary calcium intakes reduce zinc absorption and balance in humans. American Journal of Clinical Nutrition, 65, 1803-1809.

Zhang, L., Li, G., Wang, S., Yao, W. & Zhu, F. (2017). Physicochemical properties of maca starch. Food Chemistry, 218, 56-63. http://dx.doi. org/10.1016/j.foodchem.2016.08.123. PMid:27719949.

Zhang, J., Wang, H.-M., Zhao, Y.-L., Zuo, Z.-T., Wang, Y.-Z. & Jin, H. (2015). Comparison of mineral element content in a functional food maca (Lepidium meyenii Walp.) from Asia and South America. Journal of Analytical Methods in Chemistry. https://doi.org/10.1155/2015/530541.




DOI: http://dx.doi.org/10.33448/rsd-v9i6.3519

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