Epidemiological profile of people affected by botulism in Brazil between 2008 and 2018

Alison Pontes da Silva, Brenda Tamires de Medeiros Lima, Marília de Barros Cândido, Januse Millia Dantas de Araújo, Allana Brunna Sucupira Duarte, Francisco Patricio de Andrade Júnior

Abstract


Botulism presents as a bacterial infection, neuroparalytic and non-contagious infection caused by toxins produced by Clostridium botulinum, called botulinum toxins. However, even though this disease has a high lethality, there is a great lack of epidemiological studies on this topic in Brazil. Based on that, this research aimed to trace the epidemiological profile of botulism in Brazil between the years 2008 to 2018. It is an epidemiological, retrospective, analytical and documentary study, in which data were collected from the Department of Informatics of the Unified Health System. Between 2008 and 2018, 69 cases of botulism confirmed in Brazil were evidenced, with the state of São Paulo having the highest number of notifications (30.5%). The profile of those affected was mostly male (58%), low education (26%), 20 to 39 years old (47.8%), white ethnicity (59.4%), residents of the urban area ( 85.5%), contracted botulism, mainly food-type (94.2%), with the presence of AB toxins (15.9%) and clinical cure outcome (68.1%). Thus, the data present in this research can contribute to the development of indicators and public policies related to botulism.

Keywords


Botulism; Botulinum toxins; Clostridium botulinum; Epidemiology.

References


Andrade Júnior, F. P. et al. (2019). Profile of tuberculosis patients in Natal-RN, Brazil, from 2010 to 2018: a documentary study. Scientia Plena, 15(10).

Anniballi, F.; Auricchio, B.; Fiore, A.; Lonati, D.; Locatelli, C. A.; Lista, F.; Fillo, S.; Mandarino, G.; de Medici, D. (2017). Botulism in Italy, 1986 to 2015. Euro Surveillance, 22(24), 1-8.

Czerwiński, M.; Czarkowski, M. P.; Kondej, B. (2016). Foodborne botulism in Poland in 2014. Przegla̧d Epidemiologiczny, 70(2), 217-223.

Dallastra, E. D. G. et al. (2018). Botulismo, uma doença letal. DESAFIOS-Revista Interdisciplinar Da Universidade Federal Do Tocantins, 5(3), 142-150.

Eduardo, M. B. P; Madalosso, G; Paiva, O. R; Brito, S. N; Araújo, E. S; Bandeira, C. R. S; Rowlands, R. E. G.; Ristori, C. A; Jakabi, M. (2007). Botulismo tipo A e B causado por torta comercial de frango com palmito e ervilhas no município de São Paulo, SP – janeiro de 2007. Boletim Epidemiológico Paulista, 4(38).

Fonseca, K. C. O. S; Carvalho, C. W. F; Carvalho, C. V. F; Barbosa, F. R; Pereira, D. E. (2018). Botulismo de origem alimentar e suas toxinas: uma revisão literária. In: XXII Congresso Brasileiro de Nutrologia. International Journal of Nutrology.

Lindemann, I. L. et al. (2016). Leitura de rótulos alimentares entre usuários da atenção básica e fatores associados. Cadernos de Saúde Coletiva, 24(4), 478-486.

Lindström, M; Korkeala, H. (2006). Laboratory Diagnostic of Botulism. Clinica, Microbiology Reviews, 19(2), 298-314.

Nejadrahim, R.; Delirrad, M. (2016). Foodborne Botulism: A Study of 57 Cases in Northwest Iran. Iranian Journal of Toxicology, 10(6), 45-50.

Oliveira, J. F.; Brum, A. N.; Lourenção, L. G. (2019). Botulismo alimentar no Brasil, 2001-2015. Research, Society and Development, 8(12), 01-14.

Rao, A. K. et al. (2017). Clinical characteristics and ancillary test results among patients with botulism—United States, 2002–2015. Clinical Infectious Diseases, 66(1), 4-10.

Serra, F. N.; Lourenção, L. G. (2019). Botulismo em humanos: revisão clínico-epidemiológica de estudos brasileiros. Enfermagem Brasil, 18(1) ,123-132.

Silva, B. R. T. C; Pessoa, N. O. (2015). Botulismo por Clostridium botulinum na intoxicação alimentar animal e humana. Uma Revisão. Revista Brasileira de Higiene e Sanidade Animal, 9(4), 733-747.

Sobel, J; Rao, A. K. (2018). Making the best of the evidence: toward national clinical guidelines for botulism. Clinical Infectious Diseases, 66(1), 1-3.

Sposito, M. M. M. (2009). Toxina botulínica do tipo A: mecanismo de ação. Acta fisiátrica, 16(1).

Williamson, C. H. D. et al. (2017). Differentiating botulinum neurotoxin-producing clostridia with a simple, multiplex PCR assay. Appl. Environ. Microbiol., 83(18), 806-817.

Zatti, C. A. (2013) Botulismo: conhecendo os casos brasileiros notificados entre 2007 a junho de 2013. Revista Contexto Saúde, 13(24), 21-26.


Refbacks

  • There are currently no refbacks.


Base de Dados e Indexadores: Base, Diadorim, Sumarios.org, DOI Crossref, Dialnet, Scholar Google, Redib, Doaj, Latindex, Redalyc, Portal de Periódicos CAPES

Research, Society and Development - ISSN 2525-3409

Licença Creative Commons
Este obra está licenciado com uma Licença Creative Commons Atribuição 4.0 Internacional

Rua Irmã Ivone Drumond, 200 - Distrito Industrial II, Itabira - MG, 35903-087 (Brasil) 
E-mail: rsd.articles@gmail.com
Facebook: https://www.facebook.com/Research-Society-and-Development-563420457493356