Relationship of vitamin D on obesity inflammation

Stéfany Rodrigues de Sousa Melo, Raísa de Oliveira Santos, Loanne Rocha dos Santos, Jennifer Beatriz Silva Morais, Juliana Beatriz Silva Severo, Mickael de Paiva Sousa, Kyria Jayanne Clímaco Cruz, Ana Raquel Soares de Oliveira, Dilina do Nascimento Marreiro


Introduction: The literature has shown vitamin D deficiency in obese individuals, which contributes to the manifestation of low-grade chronic inflammation. Therefore, this review aims to provide updated information on the relationship of vitamin D with the inflammatory process triggered in obesity. Methodology: A bibliographic survey was performed in the Pubmed, SciELO, LILACS and Cochrane databases, using the following keywords: "vitamin D" and "inflammation"; "obesity" and "inflammation"; "vitamin D", " obesity” and“ inflammation ”. Results and Discussion: Obese individuals appear to have vitamin D deficiency due to inadequate intake or increased uptake of this vitamin by adipose tissue which may contribute to the increase of chronic low grade inflammation present in obesity. Conclusion: The inadequate intake of vitamin D contributes to the manifestation of its deficiency in obese. However, further studies are needed, considering that the metabolism of this micronutrient is not completely elucidated.


Micronutrient; Metabolism; Chronic Diseases.


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